Thursday July 28/8:00
MS41/Seabreeze
Dynamics of the Repeated Structures of the Genome
Sponsored by Society for Mathematical Biology
Many important biological phenomena are caused by gene amplification, expansion of arrays of DNA repeats and other related processes. Resistance of cancer cells to chemotherapy, evolution of gene families and hereditary diseases are some important examples. The dynamics of these phenomena has been modeled using stochastic processes and simulation programs. The speakers in this minisymposium will present a range of approaches including construction of mathematical models of dynamics, detection of repeats and other structures in the data, and optimal control of amplification processes.
Organizer: Marek Kimmel
Rice University
- 8:00: Optimization of Cancer Chemotherapy and Gene Amplification
Andrzej Swierniak, Silesian Technical University, Poland
- 8:30: Optimal Control of Somatic Hypermutation in B Lymphocytes
Alan S. Perelson, Los Alamos National Laboratory, and Thomas B. Kepler, North Carolina State University
- 9:00: Discovering Structure in Genetic Regulatory Sequences
Michiel Noordewier, Rutgers University, Piscataway
- 9:30: Dynamics of DNA Repeats in Hereditary Diseases and Cancer
Marek Kimmel, Organizer